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Abstract Activation of the key nutrient cellular sensors mTORC1 and mTORC2 directs the fate of mesenchymal stromal cells (MSCs)

Pharmacologically, KEAP1 activity can be inhibited by the compound bardoxolone (CDDO) 68

10.1093/jn/134.3.489 95

8 ROS triggered by overload of intracellular iron metabolism regulate cell death and cause senescence, which is the key mechanism of ferroptosis

Discussion Glutathione (GSH) is recognized as the most abundant and essential endogenous antioxidant, functioning as the primary non-protein thiol constituent within the ROS detoxification system in living cells [41]